Is CEA Better than CYFRA 21-1 in the Monitoring of Squamous Cell Lung Cancer Progression?

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Predictive value of CYFRA 21-1, CEA, SCC-Ag and LDH in early stages of squamous cell lung cancer

Aim: The diagnostic methods used for evaluation of the stage and extent of the malignant process have to rather limited efficiency and low predictive value in the qualification of patients to surgical resection of tumor. The presented study provides assessment of the diagnostic usefulness of CYFRA 21-1 SCC-Ag, CEA and LDH, and their predictive value for estimation of overall survival in patient...

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Carcinoembryonic antigen, squamous cell carcinoma antigen, CYFRA 21-1, and neuron-specific enolase in squamous cell lung cancer patients.

BACKGROUND Carcinoembryonic antigen (CEA), squamous cell carcinoma antigen (SCC-Ag), and CYFRA 21-1 are the most useful markers for non-small cell lung cancer (NSCLC), but neuron-specific enolase (NSE) is a tumor maker of choice for SCLC. The determination of NSE in NSCLC could allow selection of patients with neuroendocrine features. NSCLC patients whose tumors have neuroendocrine properties m...

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Prognostic value of combination of Cyfra 21-1, CEA and NSE in patients with advanced non-small cell lung cancer.

OBJECTIVE To assess the value of Cyfra 21-1, carcino-embryonic antigen (CEA) and neuron-specific enolase (NSE) combined, all three together as prognostic factors in advanced stage non-small cell lung cancer (NSCLC) patients. PATIENTS AND METHODS Serum samples from untreated NSCLC patients were prospectively collected. All assays were performed using commercial kits blind to clinical informati...

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CYFRA 21-1 is an early predictor of chemotherapeutic effectiveness in advanced nonsmall cell lung cancer

Serum cytokeratin 19 fragment (CYFRA21-1) has been found to be a useful prognostic marker in lung cancer. Previous studies have revealed that change in CYFRA21-1 synchronously predicted therapeutic effectiveness in advanced nonsmall cell lung cancer (NSCLC) after the second cycle of chemotherapy. The objective of this study was to investigate the early predictive value of percentage change in s...

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Preoperative CYFRA 21-1 and CEA as prognostic factors in patients with stage I non-small cell lung cancer.

PURPOSE This study investigated the preoperative serum levels of CYFRA 21-1 and CEA as prognostic factors in patients with stage I non-small cell lung cancer. SUBJECTS This study evaluated 341 patients who had undergone a complete resection for stage I NSCLC between 2002 and 2008. RESULTS The patients included 193 males and 148 females. The mean age of the patients was 69.2 years (range: 19...

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ژورنال

عنوان ژورنال: Medical Principles and Practice

سال: 2011

ISSN: 1423-0151,1011-7571

DOI: 10.1159/000321277